Recent Advances in Gold(I) Complexes Based Biological Applications

نویسندگان

  • Tong Shu
  • Lei Su
  • Shu-Feng Zhou
  • Khalid A. Al-Ghanim
  • Shahid Mahboob
  • Xueji Zhang
چکیده

The development of the synthesis of a wide range of Au(I) complexes reversibly promotes the advance in their practical usages, particularly, in biological applications. The formation of gold-sulfur rich protein adducts contributes to the cytotoxic nature of the gold compounds for chemotherapeutic approaches, while Au-Au interactions endow them with spectroscopic and luminescence properties. This article reviews that the recent five year progress for Au(I) complexes based biological applications, including the investigation of the development of new anticancer agents and antibacterial compounds, the application of biological imaging and the fabrication of novel sensors.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gold (I) Complexes of 2,2'-Biimidazolate Ligand: Syntheses and Spectral Properties of Hetero-polymetallic Complexes Having Ru2Au2 Core

The reaction of [Ru(L)2(H2biim)](ClO4)2 [L1 = 2,2¢-bipyridine (bpy) or L2 =  2-(phenylazo)pyridine (pap) and H2biim = 2,2¢-biimidazole] with Au(tht)Cl (tht = tetrahydrothiophene) in presence of base in methanol produced a terametallic cationic complex [{Ru(L)2(biim)}<s...

متن کامل

Recent advances in the polymerization of butadiene over the last decade

The stereospecific polymerization of conjugated dienes began in 1954 with the first catalysts obtained by combining TiCl4 or TiCl3 with aluminum-alkyls, i.e. the catalytic systems previously employed for ethylene and propylene polymerizations. Subsequently, many other catalytic systems were obtained and examined by a combination of transition metal or lanthanide compounds with appropriate alkyl...

متن کامل

Metal-based Chemical Entities: Opportunities in Chemical Biology and to Achieve Targeted Therapeutic Agents

My research interests concern mainly the study of the modes of action of metal compounds as anticancer agents and the development of novel metal-based chemical entities with possible biological applications. Besides synthetic inorganic chemistry and structural characterization of new metal complexes (mainly gold coordination and organometallic compounds), we strongly focus on an intensive biolo...

متن کامل

A Review of Recent Advances in Iron Oxide Nanoparticles as a Magnetic Agent in Cancer Diagnosis and Treatment

Aims In recent years, iron oxide nanoparticles have shown incredible possibilities in biomedical applications due to their non-toxic function in biological systems. Furthermore, these nanoparticles have multifunctional applications, such as antibacterial, antifungal, and anticancer effects in medicine due to their magnetic properties.  Methods & Materials In this article, 49 articles related t...

متن کامل

Recent advances on nano delivery of Helix mucus pharmacologically active components

Bioactive products from snail slime of “Helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. However, the poor pharmacokinetics characteristics of these natural compounds limit their use. Nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug del...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015